Which substance should a client avoid while taking imipramine?

Imipramine is a tricyclic antidepressant commonly used to treat depression and certain anxiety disorders. One significant concern when taking imipramine is the potential interaction with alcohol. Alcohol can enhance the sedative effects of imipramine, leading to increased drowsiness, dizziness, and impairment of cognitive and motor functions. Furthermore, alcohol consumption can exacerbate the emotional and psychological symptoms that the medication is intended to alleviate, potentially counteracting its therapeutic effects.

Avoiding alcohol while on imipramine is crucial for both safety and efficacy. It's important for clients to understand the risks associated with combining these substances, as it can lead to increased side effects and hinder their recovery process.

The other options do not present the same level of concern as alcohol. Caffeinated coffee may affect sleep but typically does not interact negatively with imipramine. Sunscreen is unrelated, and while artificial tears might be a consideration for dry eyes—possibly a side effect of the medication—they do not pose a direct risk when taken with imipramine. Thus, the primary substance to avoid due to its significant interaction and safety implications while taking imipramine is alcohol.