What should the nurse inform a client with major depressive disorder regarding medication continuation?

The statement indicating a 70% chance of experiencing a third episode after having two significant depressive episodes is particularly significant for clients with major depressive disorder. Research has found that individuals who have experienced multiple episodes of depression are at a higher risk for future episodes. This statistic emphasizes the chronic nature of depression and the importance of ongoing management, which may include medication.

Understanding this risk helps clients grasp the need for continued treatment and monitoring even after symptoms improve. It highlights the reality that major depressive disorder can be a recurrent condition, making it essential to adhere to prescribed treatments.

The other statements do not accurately reflect best practices regarding the long-term management of major depressive disorder. While some individuals may need to continue their medication for an extended period, usually referring to individualized treatment plans, it is not universally true that they must stay on antidepressants indefinitely or that lifestyle modifications alone are sufficient for managing their condition. Furthermore, stopping medication after just three months may not be appropriate, as many individuals may require a longer duration of treatment before considering discontinuation.