What is the recommended therapeutic serum level for lithium?

The recommended therapeutic serum level for lithium is typically between 0.6 to 1.2 mEq/L. This range has been established based on clinical evidence demonstrating its efficacy in treating bipolar disorder and managing mood stabilization while minimizing the risk of toxicity.

At levels below 0.6 mEq/L, lithium may not be sufficiently effective for mood stabilization, leading to ineffective treatment outcomes. On the other hand, serum levels above 1.2 mEq/L significantly increase the risk of adverse effects, including renal impairment, gastrointestinal distress, neurological symptoms, and thyroid dysfunction. Therefore, maintaining lithium levels within this therapeutic range is crucial for patient safety and treatment efficacy in managing mood disorders. This careful monitoring ensures the balance between therapeutic effects and potential toxicities.